IndraLab

Statements



sparser
"Other viral genes code for proteins that are also implicated in oncogenesis: viral interferon regulatory factor-1 (v-IRF-1) suppresses both type I and type II interferon responses; K13 (aka vFLIP) inhibits Fas-mediated apoptosis; viral g-protein-coupled receptor (vGPCR), a homologue of the IL-8 receptor, produces tumors when vGPCR-expressing fibroblasts are injected into nude mice [ xref – xref ]."

sparser
"Inhibition of anti-IgM-induced apoptosis by K13 may contribute to the development of KSHV-associated lymphoproliferative disorders."