IndraLab

Statements


YOD1 activates USP25. 5 / 5
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"Conversely, the overexpression of YOD1 increased USP21 protein stability in HEK293T, HeLa, and A549 cell lines (Fig. 4A, B)."

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"Specifically, we observed that YOD1 and USP21 have the ability to deubiquitinate each other, and that YOD1 can enhance the stability of USP21, while the reverse does not hold true."

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"Furthermore, YOD1 and USP21 deubiquitinate each other, with YOD1 upregulating USP21 protein stability, but not the reverse."

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"YOD1 upregulates USP21 stability, but not vice versa."

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"Our results demonstrated that YOD1 increased the stability of USP21 in all three cell lines (Fig. 4A, B)."