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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Tubulin inhibits CYLD. 2 / 2

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"This interaction inhibits HDAC6 mediated tubulin deacetylation, allowing CYLD to translocate to the perinuclear region."

19893491

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reach

"This hypothesis is supported by the observation that inhibition of tubulin deacetylation by downregulation of HDAC6 or inhibition of its activity by TSA induced a similar translocation of CYLD to the perinuclear area where it colocalized with the abundant acetylated MTs, whereas depolymerisation of MTs inhibited the translocation."

19893491

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...