IndraLab

Statements



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"Initially chlorpromazine, probably the first treatment against schizophrenia, was reported to inhibit TREK1 currents (Patel et al., 1998; Kim et al., 2017)."

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"Application of 10 muM fluoxetine, 20 muM paroxetine, 100 muM citalopram, and 30 muM chlorpromazine significantly inhibited TREK-1 currents by 28 +/- 11%, 40 +/- 9%, 31 +/- 10%, and 52 +/- 10%, respectively (p < 0.05, XREF_FIG a-c)."

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"The AA-activated K + current in corticotropes was reduced by fluoxetine, chlorpromazine, extracellular acidification, diphenylbutylpiperidine antipsychotics and the membrane permeable cAMP analog (8CP[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"TREK channels are also inhibited by chlorpromazine, local anesthetics and the antidepressant fluoxetine."

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"The phenothiazines fluphenazine and chlorpromazine (10 μM) inhibited human TREK-1 currents by 64 ± 8% and 83 ± 2%, the butyrophenone haloperidol by 59 ± 6%, and the thioxanthene flupenthixol by 84 ± 6[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"