
IndraLab
Statements
N-acetyl-L-cysteinate inhibits STAT1. 3 / 3
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3
reach
"Moreover, IRD targeted pyruvate kinase isozyme type M2 (PKM2) and suppressed its downstream p-JAK1, p-STAT1, p-STAT3, p-p65, iNOS, and COX2, which could be abolished by PKM2 agonist DASA-58 and antioxidant N-acetyl-L-cysteine, but partly be reversed by NF-kappaB activator CUT129 and JAK1 activator RO8191."