IndraLab

Statements

SNAI1 binds USP29. 7 / 7
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sparser
"Considering the pivotal roles that Snail1 plays during the development of resistance to chemotherapies, we posited that the USP29-Snail1 axis might be exploited by cancer cells in their acquisition of chemoresistance."
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sparser
"USP29 interacts with Snail1 and requires catalytic activity to stabilize Snail1."
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reach
"These observations imply the necessity of USP29 DUB activity in the regulation of Snail1, but the exact roles of USP29 mutations detected in cancer samples require further clarification.To evaluate the interaction between Snail1 and USP29, we carried out a series of co-immunoprecipitation experiments."
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sparser
"We then moved to investigate the potential interaction between USP29 and Snail1."
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sparser
"Cancer cells hijack the USP29-Snail1 axis to facilitate chemoresistance."
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sparser
"To evaluate the interaction between Snail1 and USP29, we carried out a series of co-immunoprecipitation experiments."
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reach
"We then moved to investigate the potential interaction between USP29 and Snail1."
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