IndraLab

Statements



reach
"It has been reported that USP39 promoted the growth of human hepatocellular carcinoma in vitro and in vivo ( Yuan et al., 2015 )."

reach
"In particular, USP39 de-ubiquitinates and stabilizes CHK2 to regulate the DNA damage response and chemical radiation resistance [43], de-ubiquitinates and stabilizes the SP1 protein to promote hepatocellular carcinoma progression [44], and inhibits VEGF-A165b-selective splicing by regulating SRSF1 and SRPK1 to promote malignant proliferation and angiogenesis of renal cell carcinoma [45]."

reach
"USP39/SMC4 promotes hepatoma cell proliferation and 5-FU resistance."