IndraLab

Statements

USP2 activates cell migration. 3 / 3
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"As shown in Figures 4(a) and (b), USP2 shRNA transfection uniformly enhanced H1299 and A549 cell migration and invasion, while USP2 overexpression vector transfection significantly suppressed the migrative and invasive capability of cancer cells.Subsequent wound healing assay suggested that H1299 cells with USP2 shRNAs transfection elevated cancer cell migration and wound healing after 48 h of incubation (Supplementary Figure 2 A-B)."
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"It is upregulated in various malignancies, such as triple negative breast cancer [17] and choroidal melanoma [18] and USP2 overexpression stimulates cell migration and invasion."
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"USP2 promotes cell migration and invasion in triple negative breast cancer cell lines."
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