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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP11 activates RAE1. 2 / 2

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"As USP11 does not regulate the RAE1 protein levels (XREF_FIG) we wondered whether USP11 modulates the association of RAE1 with the mitotic spindle."

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"We show here for the first time that upon USP11 knock-down a ubiquitinated form of RAE1 is present on the mitotic spindle resulting in a phenotype similar to RAE1 ablation, which can be partially restored by combined NuMA and USP11 knock-down."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...