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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP18 decreases the amount of BCL2L11. 2 / 2

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"Specifically, USP18 inhibition in INS-1E cells enhanced BIM expression level in untreated and IFNgamma treated conditions."

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"XREF_BIBR, XREF_BIBR, XREF_BIBR USP18 inhibition in INS-1E cells induced Bim expression in untreated and IFNalpha treated conditions (XREF_FIG), whereas DP5 (XREF_FIG) and PUMA (XREF_FIG) mRNA expression was significantly upregulated when USP18 silenced cells were exposed to IFNalpha."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...