IndraLab

Statements


USP13 increases the amount of extracellular matrix. 4 / 4
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"In summary, USP13 is a positive regulator of Smad4 stability and promotes ECM expression in lung fibroblast cells."

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"To investigate the molecular mechanisms by which USP13 modulates ECM expression, we focused on the role of USP13 on Smad4 expression."

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"The results indicate that USP13 promotes ECM expression by stabilizing Smad4 in lung fibroblasts and plays a role in the maintenance of the extracellular matrix in lungs."

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"In this study, we identify that USP13 promotes ECM expression by stabilizing Smad4 in lung fibroblast cells."