IndraLab

Statements


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"Furthermore, it has been demonstrated that in M-phase cells Rap80 exists in complex with the BRCA1, BARD1, BRCC36, and BRCC45 complex which is very abundant and its association is dependent on BRCC36 [XREF_BIBR]."

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"Fifth, through reconstitution of the BRCA1, BARD1, BRCC36, and BRE complex it demonstrates a role for BRCC36 and BRE in modulation of BRCA1 and BARD1 E3 ubiquitin ligase activity."