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MYSM1 deubiquitinates STING1. 4 / 4
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"In addition, UB-K63-mediated polyubiquitination of STING was attenuated by purified MYSM1 ( Figure 3 K)."
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"In HEK293T cells, MYSM1 deubiquitinates STING but not STING(K150R) ( Figure 3 M)."
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"Since MYSM1 deubiquitinates STING, the effect of MYSM1 on the dimerization and aggregation of STING was evaluated."
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"<span class="match term0">MYSM1</span> subsequently interacts with <span class="match term1">STING</span> and cleaves <span class="match term1">STING</span> K63-linked ubiquitination to suppress cGAS-<span class="match term1">STING</span> signaling"
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