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ALYREF inhibits USP3. 1 / 1

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"MYCN, a stable oncogenic transcription factor, is tightly regulated by the ubiquitin-proteasome system and partially relies on ALYREF for promoting enhanced cancer cell viability and proliferation [49], while ALYREF inhibits MYCN degradation by directly transcribing USP3 at levels necessary to facilitate tumor growth."

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IndraLab

Statements

ALYREF inhibits USP3. 1 / 1

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