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CHEK1 activates ATXN3. 2 / 2

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"To clarify whether Chk1 is a direct target of ATX3, we determined if the two proteins co-purify in immunoprecipitation experiments using ectopically expressed tagged proteins in human 293T cells."

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"Our data demonstrate ATX3 to be a novel regulator of Chk1 stability, supporting a critical role of ATX3 in genome integrity maintenance via Chk1 stabilization."

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IndraLab

Statements

CHEK1 activates ATXN3. 2 / 2

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