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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

CHEK1 activates ATXN3. 2 / 2

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"To clarify whether Chk1 is a direct target of ATX3, we determined if the two proteins co-purify in immunoprecipitation experiments using ectopically expressed tagged proteins in human 293T cells."

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"Our data demonstrate ATX3 to be a novel regulator of Chk1 stability, supporting a critical role of ATX3 in genome integrity maintenance via Chk1 stabilization."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...