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USP22 activates FASN. 3 / 3
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"Together, these results support that USP22 promotes CRC cell proliferation and tumorigenesis by stabilizing FASN."
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"We next investigated the role of USP22-mediated stabilization of FASN in CRC cell proliferation and tumor growth."
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"While overexpression of USP22 stabilized FASN in 293T cells (Fig. 3B), USP22 depletion promoted FASN degradation in CRC cells under CHX treatment (Fig. 3C)."
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