IndraLab

Statements

BRD4 binds UCHL3. 5 / 5
2 | 2 1
reach
"Further investigation also showed the endogenous BRD4 binding with UCHL3 which was enhanced by rIL6 but inhibited by pacritinib (Figs."
34290255
biogrid
No evidence text available
35987950
biogrid
No evidence text available
32416067
sparser
"Compared with non-phosphorylated BRD4, phosphorylated BRD4 preferentially interacts with UCHL3 and thus avoiding ubiquitination degradation mediated by UCHL3."
40691601
reach
"Of note, our experiments were performed in the presence of IL6/8. whether other deubiquitinases are preferential in other contexts need to be further investigated.To investigate if UCHL3 binds to BRD4, we performed reciprocal co-immunoprecipitation assays in cells transfected with BRD4, alone or with UCHL3 and JAK2-V617F."
34290255