IndraLab

Statements

PNA1 binds USP6. 3 / 3
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"Next, we tested the binding of PNA1 to HRP1 at physiological pH (XREF_TABLE, entry 6)."
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"In our experimental system, binding of RNA and PNA1 to HRP1 resulted in similar changes in the CD signal, decrease at 240-260 nm and increase at 280-290 nm, which were fully consistent with the CD spectra previously observed for the triple helical binding of cytosine rich PNA to double stranded DNA."
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"Finally, the CD spectra of RNA and PNA1 bound to HRP1 were fully consistent with previous results on PNA-DNA triple helices."
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