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DAXX activates USP7. 2 / 4

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"These findings suggest that Daxx directs HAUSP toward its associated protein MDM2, to increase MDM2 activity towards p53 (Tang, Qu, & Zhang, 2006)."

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"In addition, the death domain-associated protein DAXX was shown to bind simultaneously to Mdm2 and USP7 and to mediate the stabilizing effect of USP7 on Mdm2 [12] ."

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DAXX activates USP7. 2 / 4

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