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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

DAXX activates USP7. 2 / 4

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"These findings suggest that Daxx directs HAUSP toward its associated protein MDM2, to increase MDM2 activity towards p53 (Tang, Qu, & Zhang, 2006)."

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"Deubiquitination by USP7 stabilizes p53 and MDM2, with the adaptor protein Daxx directing USP7 to MDM2."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...