IndraLab

Statements

KCNH2 binds NEDD4L. 8 / 8
2 | 5 1
reach
"Our data demonstrate that Cav3, hERG, and ubiquitin-ligase Nedd4-2 interact with each other and form a complex."
22879586
sparser
"Ye at al [ xref ] do not report whether changes in channel membrane expression are involved in CAV3 -V37L-associated I Kr downregulation; however, loss of Cav-3 contribution to hERG-NEDD4–2 interaction would increase I Kr instead."
32634502
reach
"As shown in Fig. 3 C, a specific signal for Nedd4-2 was found when ERG1 was immunoprecipitated, thus indicating an interaction between ERG1 and Nedd4-2 in the guinea pig heart.We investigated whether [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21463633
reach
"Here, we provide evidence of an interaction between hERG1 and Nedd4-2 in guinea pig hearts, suggesting that ubiquitylation of the channel by this ubiquitin ligase could play a role in its regulation i[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21463633
reach
"The biochemical interactions between hERG1 and Nedd4-2 were investigated by co-immunoprecipitation experiments."
21463633
reach
"Similar to Nedd4-2, WWP2 but not Nedd4-1 was present in the fraction immunoprecipitated with the anti-hERG1 antibody, when expressed with the WT channel, demonstrating that hERG1 can interact both wit[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21463633
biogrid
No evidence text available
22879586
biogrid
No evidence text available
24688054