IndraLab

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USP8 ubiquitinates MAP3K7. 2 / 2

| 2

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"Overexpressed METTL3 increased MALAT1 expression through m A modification, and then MALAT1 directly bound with PTBP1 to down-regulated USP8, which resulted in reduced ubiquitination of TAK1 [75]."

37227534

➶

reach

"METTL3 increased MALAT1 levels through m A methylation to downregulate USP8; the reduced USP8 decreased TAK1 ubiquitination and degradation, which promoted macrophage pyroptosis and inflammation."

36138023

INDRA sources:

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IndraLab

Statements

USP8 ubiquitinates MAP3K7. 2 / 2

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