IndraLab

Statements


FOXP3 decreases the amount of USP25. 2 / 2
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"We have screened 2640 compounds and identified the gut microbial metabolite gallic acid, which promotes Foxp3 degradation and T reg instability by repressing Usp21 gene transcription."

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"Then, USP21 prevents Foxp3 degradation, which further enhances the transcription of Usp21 and suppresses Th1 like phenotypes."