IndraLab

Statements


USP25 activates MAP2K2. 3 / 3
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"In addition, Li et al. [13]reported that USP21 promoted HCC tumor growth by stabilizing the MEK2 protein."

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"In cycloheximide chase experiments, we next showed that the overexpression of USP21 prolonged the half-life of MEK2."

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"To gain mechanistic insights into USP21 function in HCC, we asked whether USP21 can modulate MEK2 stability in HCC derived tumor cells."