IndraLab

Statements

USP44 activates NCOR. 2 / 2
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reach
"The N and CoR complex is a well documented co-repressor for unliganded nuclear receptors, and our data demonstrate that USP44 contributes to NCoR mediated repression of the PPARdelta target gene Angptl4."
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"Similarly, the deletion of USP44, an integral component of NCoR, impaired the ability of NCoR to regulate gene expression and suppressed breast cancer cell invasiveness [29]."
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