IndraLab

Statements

reach
"OTUD5 promotes innate antiviral and antitumor immunity through deubiquitinating and stabilizing STING."
32879469
reach
"This is highlighted in antigen-stimulated macrophages, in which pSer177 DUBA levels are increased to regulate the immune response."
26073511
reach
"25 OTUD5 enhanced anti‐viral infection and anti‐tumor immunity by stabilizing STING."
39721018
reach
"Our previous study indicated that OTUD5 promotes innate antiviral and antitumor immunity by removing K48-linked ubiquitin chains of STING and strengthening its stability [33]."
38605168
reach
"The experimental data obtained from knockout mouse models clearly indicate that the lack of OTUD5 leads to heightened vulnerability to viral infections and accelerated melanoma progression, highlighting the crucial function of OTUD5 in STING-mediated immunity [21]."
39558334