IndraLab

Statements


OTUD7B inhibits C4B_2. 3 / 3
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"Phenylephrine‐induced CH potentiated by OTUD7B knockdown was completely blocked by the upregulation of KLF4 activity."

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"Notably, OTUD7B suppressed CH progression by activating AKT signaling cascades and regulating KLF4 (Krüppel‐like factor 4) degradation."

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"Similarly, we observed that OTUD7B overexpression attenuated TAC‐induced CH in gain‐of‐function studies."