IndraLab

Statements

USP17L2 deubiquitinates SNAI1. 9 / 10
1 | 9
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"DUB3 promotes breast cancer metastasis by deubiquitinating Snail [35]; thus, we further explored the mechanism by which USP30 regulates Snail."
38146008
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"DUB3 activation mediated by CDK4 and 6 is very important for the deubiquitination and stabilization of SNAI1."
39538371
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"Such as, the snail is deubiquitinated and stabilized by PSMD14, DUB3, and USP26 [29–31]."
36424389
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"Collectively, these data confirmed that NXN could competitively interrupt the association between DUB3 to bind with Snail and inhibited the deubiquitylation of Snail by DUB3, thereby stabilizing Snail and enhancing HCC metastasis."
35927236
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"So far, DUB3 is the only deubiquitinating enzyme that has been demonstrated to deubiquitinate and stabilize SNAIL."
29331416
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"In addition, several discoveries have been made about the de-ubiquitination of EMT-TFs, i.e., Dub3 de-ubiquitinates Snail [59], Slug and Twist [22], whereas Trabid stabilizes Twist by cleaving RNF8-induced ubiquitination [21] and USP29 cooperates with phosphatase SCP1 to stabilize Snail [60]."
36732432
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"DUB3 is a deubiquitinating enzyme that has been reported to deubiquitinates and stabilizes Snail, and it is one of cytokine induced DUBs [ 23 , 24 ]."
30763716
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"Given that Snail could be deubiquitinated and stabilized by DUB3, we explored the relationships among NXN, Snail and DUB3 in HCC cells [9, 19]."
35927236
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"Similar to the regulatory mechanism in previous studies, we identified that NXN competitively interrupted the association between DUB3 to bind with Snail and inhibited deubiquitylation of Snail by DUB3, thereby stabilizing Snail and enhancing HCC metastasis."
35927236