IndraLab

Statements

Lidocaine inhibits SCN5A. 6 / 6
1 1 | 1 3
reach
"The concentration dependence of the lidocaine block of hH1 Na current was consistent with a binding stoichiometry of 1:1."
1336062
reach
"In contrast, lidocaine markedly reduced hH1 I Na after a prepulse to -100 mV."
10620286
eidos
"Further investigations indicated that blocking NaV1.5 by lidocaine or sodium ion channel blocker decreased the ovarian malignancy through inactivation of FAK / Paxillin signaling pathway ( Figure 7 ) ."
33280262
dgi
No evidence text available
ctd
No evidence text available
23261645
reach
"When expressed in Xenopus oocytes, lidocaine block of hH1 (human cardiac) Na current greatly exceeded that of mu1 (rat skeletal muscle) at membrane potentials near V (rest), whereas hyperpolarization to -140 mV equalized block of the two isoforms."
10620286