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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP7 decreases the amount of ATF3. 1 / 1

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"While USP7 inhibition could result in downregulation of MDM2 19 thereby preventing ATF3 from MDM2 mediated ubiquitination and degradation 28, it might also be that the increased ATF3 expression was caused by USP7 catalyzed deubiquitination of ATF3."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...