IndraLab

Statements

USP18 activates Infections. 3 / 3
| 3
reach
"We found that USP18 increased HIV-1 infection by more than 40-fold and HIV-2Δvpx by over 7-fold."
| PMC
reach
"Knockout of USP18 abrogated significantly the infection of HIV-1 by more than 6-folds, which correlated strongly with reduced phosphorylated SAMHD1.USP18 blocked the interferon-induced signalling in the THP-1 cells measured by ISG induction by real time PCR."
| PMC
reach
"CRISPR/Cas9 knockout of USP18 enhances type I IFN responsiveness and restricts HIV-1 infection in macrophages."
29437254