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Statements

BRCC3 inhibits chloroethene. 7 / 7
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"After overexpression of BRCC36, VC was reduced and β-catenin pathway activation was inhibited (β-catenin phosphorylation decreased), suggesting that BRCC36 inhibited VC by inhibiting β-catenin pathway[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"We aimed to elucidate the possible role and underlying molecular mechanisms of BRCC36 in VC and revealed that BRCC36 attenuated VC in CKD mice and inhibited the osteogenic differentiation of VSMCs in calcifying medium (CM)."
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"BRCC36 inhibits VC via the Wnt/beta-catenin signalling pathway."
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"Conversely, treatment with MSAB (a β-catenin selective inhibitor) attenuated BRCC36 silencing-enhanced VC (Fig. 4J, K)."
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"In this study, the expression of BRCC36 was found to be significantly decreased in both in vivo and in vitro VC models, while overexpression of BRCC36 reduced VC in rat VSMCs.The β-catenin signalling [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"This provides a material basis for us to continue to study the molecular mechanism of BRCC36 on the regulation of β-catenin post-translational modification.However, our study has the following shortco[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"BRCC36 overexpression inhibited VC."
35149088