IndraLab

Statements

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"OTUD1 upregulation suppressed cell viability and invasion and migration via mediating stabilization of KLF4, while silencing of OTUD1 showed the opposite effect [148] ."
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"A CCK‐8 assay was employed to illustrate that overexpression of KLF4 effectively reduced cell viability increased by knockdown of OTUD1 (p < 0.01, Figure 6b)."
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"Depletion of endogenous OTUD1 potentiated the capacity of RAS transformed MCF10A cells to form tumor organoids in 3D Matrigel but did not inhibit tumor cell survival and proliferation under standard 2D culture conditions."
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"CCK‐8 assay showed that OTUD1 knockdown dramatically upregulated the cell viability of PC9 and A549 cells (p < 0.01, Figure 3b)."
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