IndraLab

Statements



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"Hydroxychloroquine reversed the aPL-inhibition of trophoblast IL-6 secretion and partially limited aPL-inhibition of cell migration."

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"Recently, in vitro studies (Albert et al., 2014; Marchetti et al., 2014) have demonstrated that HCQ reverses the aPL inhibition of trophoblast interleukin-6 secretion and partially limits aPL inhibition of cell migration, as well as restores trophoblast differentiation affected by anti-β2GP1 antibodies."

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"In contrast, HCQ and 2-DG alone similarly reduced cell migration compared with the control, and their combination significantly inhibited cell migration in 4T1 cells (Fig. 2B, C)."