IndraLab

Statements

USP19 inhibits autophagy. 3 / 3
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"We found that levels of p62 reduced as processed LC3B-II levels increased in USP19KO cells, suggesting that loss of USP19 could lead to altered autophagy (Fig. 2, E and F)."
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"USP19 inhibited NLRP3 inflammasome activation by increasing autophagy flux and decreasing the generation of mitochondrial reactive oxygen species."
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"We next investigated whether USP19 loss could lead to altered lysosomal function and/or autophagy."
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