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Carbon monoxide inhibits EIF2AK1. 2 / 2

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"HRI is activated by NO binding to the heme, which displaces both endogenous ligands, but HRI is inhibited by formation of the 6-coordinate CO adduct."

19405475

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"Other investigators reported that CO directly inhibited the kinase activity of HRI in vitro [51,52]."

28347842

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IndraLab

Statements

Carbon monoxide inhibits EIF2AK1. 2 / 2

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