IndraLab

Statements

P5091 activates cell death. 4 / 4
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"Annexin V staining likewise demonstrated P5091 induced cell death in TP53 wild-type Ewing sarcoma cell lines (XREF_FIG)."
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"This suggests that, as in other malignancies, P5091 can also induce GBM cell death."
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"In addition, P5091, besides working synergistically with conventional treatment drugs, induces cell death of multiple myeloma cells that are resistant to the standard therapy."
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"The role of HDM2 during P5091 induced cell death was further examined using p53 -/- and p53 -/- / MDM2 -/- (double KO) mouse embroyonic fibroblasts (MEFs)."
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