IndraLab

Statements

BAP1 deubiquitinates VHL. 1 / 1

| 1

reach

"However, this might not remain true in malignancies in which the VHL gene (34)—or other genes that suppress HIF-1α (10)—are also mutated and thus display constitutively high levels of HIF-1α, which may overrun the fine-tuning BAP1 deubiquitylating activity.In addition to VHL, which is active in normoxia, other proteins mediate the ubiquitylation of HIF-1α in hypoxia."

36656861

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

BAP1 deubiquitinates VHL. 1 / 1

INDRA sources:

Databases

Reading