IndraLab

Statements


USP15 deubiquitinates SMAD2_3. 2 / 2
| 2

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"USP15 has been reported to reverse SMAD2/3 monoubiquitylation, which targets the DNA binding domains of SMAD2/3 and inhibits promoter recognition."

reach
"Upon TGFbeta signaling, Usp15 deubiquitinates Smad2/3, which would lead to p97 dissociation and transcription activation."