IndraLab

Statements

USP39 inhibits PARP1. 3 / 4
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"Moreover, depletion of USP39 blocked activation of Akt, mTOR, p53, and PARP signaling pathways."
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"USP39 overexpression impedes PARP and Caspase3 activation, diminishing the apoptotic rate in ESCC cells treated with cisplatin [53]."
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"Silencing USP39 expression hinders MGC-803 GC cell proliferation and induces G2/M arrest and PARP cleavage [60]."
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