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"On the other hand, LPSinduced IL-8 production by human monocytes is suppressed by CAM through NF- B and AP-1.19 Although it can not be denied that CAM affects activation of AP-1, those findings suggest that the transcriptional factors responsible for the expression of IL-8 vary with the stimulants and the cells chosen for the experiment.CONCLUSION The present study demonstrates that expression ofboth IL-8 protein and mRNA in adenoidal fibroblasts is induced by HIE and IL-1 ."