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D-threo-isocitric acid inhibits KCNH2. 2 / 2

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"Carvedilol (nonselective), propranolol (nonselective) and ICI 118551 (beta (2)-selective) inhibited HERG current in a concentration dependent manner (IC (50) 0.51, 3.9 and 9.2 microM, respectively)."

16314852

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"Inhibition of HERG current by carvedilol, propranolol and ICI 118551 was partially but significantly attenuated in Y652A and F656C mutant channels."

16314852

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IndraLab

Statements

D-threo-isocitric acid inhibits KCNH2. 2 / 2

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