IndraLab

Statements

USP7 inhibits KMT2E. 2 / 2

| 2

reach

"Thus, OGT, USP7 and MLL5 form a highly organized protein complex through specific interactions among domains, and the absence of either USP7 or OGT leads to enhanced ubiquitylation and accelerated degradation of MLL5 protein."

26678539

➶

reach

"Absence of either OGT or USP7 triggers rapid degradation of MLL5 proteins via the ubiquitin-proteasomal pathway."

26678539

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

USP7 inhibits KMT2E. 2 / 2

INDRA sources:

Databases

Reading