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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP7 inhibits KMT2E. 2 / 2

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"Thus, OGT, USP7 and MLL5 form a highly organized protein complex through specific interactions among domains, and the absence of either USP7 or OGT leads to enhanced ubiquitylation and accelerated degradation of MLL5 protein."

26678539

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"Absence of either OGT or USP7 triggers rapid degradation of MLL5 proteins via the ubiquitin-proteasomal pathway."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...