IndraLab

Statements



reach
"Furthermore, SP600125 also significantly inhibited secretion of IFN-beta (XREF_FIG) suggesting that Poly I : C induced IL-1beta, TNFalpha, IL-12p70 and IFN-beta production in keratinocytes is mediated by JNK signaling pathway."

reach
"In this study, JNK inhibitor SP600125 prevented the upregulation of IL-1beta, TNFalpha, IL12p70 and IFN-beta upon stimulation with Poly I : C, suggesting that intracellular signaling by the JNK pathway contributes to regulation of proinflammatory cytokines and type I IFN."