IndraLab

Statements

USP22 increases the amount of ABCC1. 4 / 4
| 4
reach
"LY294002 (10mum) also suppressed USP22 induced high expression of MRP1 via inhibition of AKT pathway in BEL7402 cells."
28417539
reach
"Subsequently, using qPCR array analysis, we found that knockdown of USP22 could drastically inhibit the expression of MRP1, but not P-gp, in BEL/FU cells."
28417539
reach
"Collectively, USP22 might deubiquitinate SIRT1 and subsequently activate the AKT pathway, increasing the expression of MRP1 to induce MDR in HCC cells."
28417539
reach
"During sorafenib treatment, upregulation of USP22 increases ABCC1 expression and subsequently contributes to sorafenib resistance in HCC cells."
35203285