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NCOR2 inhibits USP17L2. 2 / 2

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"The NCOR2 gene is frequently deleted in castration resistant prostate cancer patient specimens, and loss of NCOR2 induces elevation of DUB3 and BRD4 proteins in cancer cells."

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"Using a gain-of-function approach, we demonstrated that overexpression of BRD4 elevated NCOR2 expression but repressed DUB3 at both the mRNA and protein levels in C4-2 cells."

30057199

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Statements

NCOR2 inhibits USP17L2. 2 / 2

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