IndraLab

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"Using a gain-of-function approach, we demonstrated that overexpression of BRD4 elevated NCOR2 expression but repressed DUB3 at both the mRNA and protein levels in C4-2 cells."

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"Similarly, NCOR2 loss in prostate cancer increases BRD4 deubiquitinase DUB3 and thus induces elevation of BRD4 protein."