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Heparin inhibits CTSL. 3 / 5
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"We show that heparin reduces the stability of the pro form of cathepsin L at pH 5 by binding to a putative heparin binding motif (BBXB) in the pro domain."
18086562
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"The presence of heparin accelerated inhibition of cathepsin L by both serpins, and in the case of SCCA-1, heparin increased the second order inhibition rate constant from 5.4 x 10 (5) to> 10 (8), indicating a rate enhancement of at least 180-fold."
19959474
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"For example, the glycosaminoglycan heparin, a known anti-coagulant, enhances inhibition of cathepsin L by serpin B3 and B4."
29632742