IndraLab

Statements



reach
"Moreover, either ATRA or Pin1 knockdown significantly suppressed R848 induced IRF-7 transactivation, as shown by the luciferase reporter assay (XREF_FIG), and also blocked R848 induced nuclear translocation of IRF-7, as shown by immunostaining (XREF_FIG)."

reach
"As shown in XREF_FIG, ATRA at 5 muM effectively induced Pin1 degradation, suggesting that ATRA might inhibit Pin1 dependent IRAK-1 and IRF-7 signaling."