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"Recently, loss-of function mutations in KCND3 (potassium voltage gated channel, Shal related subfamily, member 3) have been identified causing SCA19/22 [XREF_BIBR, XREF_BIBR], whereas gain-of function mutations in KCND3 were implicated in Brugada syndrome and atrial fibrillation [XREF_BIBR - XREF_BIBR]."