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EMMAA Bob with Bioagents

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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

PDE4B inhibits CYLD. 4 / 6

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"Moreover, PDE4B negatively regulates CYLD via selective activation of JNK2 but not JNK1."

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"PDE4B downregulates CYLD via activation of JNK2 pathway."

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"Moreover, PDE4B negatively regulates CYLD via specific activation of JNK2 but not JNK1."

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"For example, inhibiting PDE4B in an HMEEC cell line caused an upregulation of CYLD and a concomitant reduction in inflammation [XREF_BIBR]."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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