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USP7 deubiquitinates CHFR. 7 / 7
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"For example, USP7 mediates the deubiquitination of the checkpoint protein CHFR."

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"It is reported that USP7 can mediate the deubiquitination of CHFR protein, and the E3 enzyme activity of CHFR protein can target Aurora-A kinase for ubiquitination-dependent protein degradation."

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"Thus, we examined whether USP7 can mediate the deubiquitination of Chfr in vivo."

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"These results demonstrate that USP7 preferentially functions in deubiquitination of Chfr, and prevents autoubiquitination mediated degradation of Chfr.The present study has demonstrated that Chfr bind[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Deubiquitination of Chfr, a checkpoint protein, by USP7 and HAUSP regulates its stability and activity."

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"Ubiquitin specific protease, USP7 and HAUSP deubiquitinates CHFR and prevents its degradation, resulting in the increased stability [9]."